Anime — Elfen Lied

It's a comedic harem anime with the same motif as Love Hina — the male set up as a guesthouse caretaker, and the guesthouse fills up with girls. Only this time some of them are telekinetics with the habit of blowing people up in gory explosions, when not being delightfully clueless, in a manner reminiscent of Chobits trainwrecked with Scanners.

It's a wonder this hasn't garnered the nickname “Love Lucy”, based on the name of the main telekinetic girl character.

Conspiracy, violence, gore, and nudity — only in Japan (the Yanks would have blurred out the nipples).