It starts off with an offbeat premise -- a boy who can see microbes, and whose family has associations with the brewing trade, going up to agricultural college; such plot as there is generally involves weird and wonderful fermented foodstuffs from around the world (like kiviak, illustrated on the right); and the intricacies of sake production.
It's only 11 episodes, and could have been fluffy and slightly educational with it; and after 6 episodes, I was willing to rate it as "unexpectedly good". But then the next two episodes got subbed...
-- after the half-way point, the gross fermented foodstuffs give way to frat-boy antics, sophomoric ecchi humour, and bolt-on by-the-numbers fan-service (trap? check. lipstick lesbians? check.) -- which literally loses the plot. It wasn't about the people, it was about fun with fermentation, and related bio-industrial or similar processes.